The objective of the present study was to develop the delayed release multi-particulate pellet formulation of Rosuvastatin Calcium to improve the distribution of Rosuvastatin calcium, improve the product stability and to modulate the release properties. In the present study delayed release multi-particulate pellet formulation of Rosuvastatin Calcium was prepared by using fluidized bed coating method. Different pellet formulations were made by using delayed release rate controlling polymer like Eudragit L 30 D 55 and finally tablets were made. All the Prepared formulations were evaluated for the physical characteristics, in vitro dissolution and stability at 40°C/ 75% RH for three months. The release of Rosuvastatin calcium from the tablet for a period up to 10 hrs was recorded in controlled manner. The model for analysis of final formulation fitted showed that the release of Rosuvastatin Calcium follows delayed release.
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